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[The role of genome repetitive sequences in primary hypertension]
D V Bebikhov1, T A Nikonenko, A Iu Postnov
1Cardiological Research-Industrial Complex, Moscow, Russia.
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
|January 22, 2000
Abstract:
Genetic determining factors of essential hypertension seems to involve a dynamic mutation or a similar process. The mobile elements of the genome: moderately recurrent sequences, play a special role in initiation of such a process. A possible molecular mechanism of the initiation and development of the dynamic mutation, is described.