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On the wobble GoU and related pairs
1Institut de Biologie Moléculaire et Cellulaire du CNRS, UPR9002, Strasbourg, France.
Abstract:
The wobble GoU pairs have been implicated in several biological processes where RNA molecules play a key role. We review the geometrical and conformational properties of wobble GoU pairs on the basis of available crystal structures of RNAs at high resolution. The similarities with the wobble A+oC pairs and UoU pairs are illustrated, while the differences with the recently discovered bifurcated G x U pairs are contrasted.