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Related Experiment Videos

Aortic root dilation prior to valve opening explained by passive hemodynamics.

I Vesely1

  • 1Department of Biomedical Engineering, The Lerner Research Institute, The Cleveland Clinic Foundation, Ohio 44195, USA.

The Journal of Heart Valve Disease
|March 4, 2000
PubMed
Summary

Aortic root dilation occurs passively before the aortic valve opens, driven by hemodynamics, not active contractile elements in the valve or aortic wall.

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Area of Science:

  • Cardiovascular Physiology
  • Biomechanical Engineering

Background:

  • The mechanism of aortic valve opening and aortic root dynamics has been debated.
  • A hypothesis suggested contractile elements within the aortic valve contribute to its function.

Purpose of the Study:

  • To propose a purely passive mechanism for aortic root dilation.
  • To explain aortic root expansion based on passive hemodynamics.

Main Methods:

  • Analysis of previous cine fluoroscopy and sonomicrometry studies.
  • Simplified force calculations to understand mechanical interactions.

Main Results:

  • Aortic root expansion of 5-7% occurs before valve opening.
  • Mechanical interactions create an inward pull on commissures, limiting initial dilation.

Related Experiment Videos

  • Reduced inward pull as ventricular pressure rises allows full aortic dilation.

    • Conclusions:

    • Aortic root dilation prior to valve opening is a passive process.
    • No active mechanism within the aortic valve leaflets or aortic wall is required.