Related Experiment Videos
Tyrosine kinase SYK: essential functions for immunoreceptor signalling
M Turner1, E Schweighoffer, F Colucci
1Molecular Immunology Programme, The Babraham Institute, Cambridge, UK CB2 4AT. martin.turner@bbsrc.ac.uk
Immunology Today
|February 26, 2000
Abstract:
The tyrosine kinase SYK plays critical roles in signalling through immune receptors. Gene-targeting studies have identified the cell types that require SYK for development and function, and the receptors that use SYK as well as their downstream signalling effectors. There is also evidence of a role for SYK in non-immune cells and in the maintenance of vascular integrity.