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Common complications of advanced cancer
K A Nelson1, D Walsh, O Abdullah
1Harry R. Horvitz Center for Palliative Medicine, the Department of Hematology/Medical Oncology, and the Taussig Cancer Center, The Cleveland Clinic, OH 44195, USA.
Seminars in Oncology
|March 4, 2000
Summary
Cancer complications, including central nervous system issues and bone metastases, are frequent. These can lead to significant patient morbidity through endocrine, hematologic, and gastrointestinal problems.
Area of Science:
- Oncology
- Cancer Research
- Internal Medicine
Background:
- Cancer and its treatments frequently cause complications.
- Complications increase in severity as cancer progresses.
- These issues significantly impact patient morbidity.
Purpose of the Study:
- To review common cancer-related complications.
- To highlight the impact of central nervous system and bone metastases.
- To discuss endocrine, hematologic, and gastrointestinal complications.
Main Methods:
- Literature review of cancer complications.
- Analysis of complication incidence and severity.
- Categorization of common oncologic emergencies.
Main Results:
- Central nervous system complications affect 15-20% of patients.
- Up to 75% of patients develop bone metastases.
- Endocrine, hematologic, and GI issues are prevalent.
Conclusions:
- Cancer complications are a significant clinical challenge.
- Effective management of complications is crucial for patient care.
- Further research is needed to mitigate treatment-related toxicities.