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Semiinvasive pulmonary aspergillosis: CT and pathologic findings in six patients
1Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Objective:
We describe the chest CT and pathologic findings of semiinvasive pulmonary aspergillosis in six patients.
Conclusion:
Semiinvasive pulmonary aspergillosis should be considered in the mildly immunocompromised patient with CT findings that reveal persistent parenchymal abnormalities. Patterns include consolidation and mass.
Insights
Semiinvasive pulmonary aspergillosis, a fungal infection, can present with persistent lung abnormalities on CT scans. This condition warrants consideration in mildly immunocompromised individuals, with common CT findings including consolidation and mass.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- Pulmonary aspergillosis encompasses a spectrum of fungal infections caused by Aspergillus species.
- Semiinvasive pulmonary aspergillosis (SIPA) is a distinct clinical entity within this spectrum.
Purpose of the Study:
- To detail the chest computed tomography (CT) and histopathologic findings in patients diagnosed with SIPA.
- To enhance the recognition of SIPA in clinical practice.
Main Methods:
- Retrospective review of six patients with pathologically confirmed SIPA.
- Analysis of chest CT imaging characteristics.
- Correlation of imaging findings with pathologic results.
Main Results:
- Chest CT scans revealed persistent parenchymal abnormalities in all patients.
- Common imaging patterns included consolidation and mass-like lesions.
- Histopathologic examination confirmed invasive fungal elements consistent with Aspergillus.
Conclusions:
- SIPA should be considered in mildly immunocompromised patients presenting with specific CT findings.
- Persistent consolidation and mass on CT scans are key indicators of SIPA.
- Radiologic-pathologic correlation is crucial for accurate diagnosis of SIPA.