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Purification of High Yield Extracellular Vesicle Preparations Away from Virus
Published on: September 12, 2019
Fatty acid-depleted albumin induces the formation of echovirus A particles
T Ward1, R M Powell, Y Chaudhry
1Division of Virology, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G11 5JR, United Kingdom.
Journal of Virology
|March 9, 2000
Abstract:
Picornavirus infection requires virus uncoating, associated with the production of 135S "A" particles and 80S empty particles from 160S mature virions, to release the RNA genome into the cell cytoplasm. Normal albumin inhibits this process. We now show that when depleted of fatty acids, albumin induces the formation of echovirus A particles.
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