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In vitro evaluation study of the membrane autotransfusion system experimental prototype: MATS-I
K Fukunaga1, T Shimoyama, K Sawada
1Department of Internal Medicine IV, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
Artificial Organs
|March 16, 2000
Summary
A new Membrane Autotransfusion System (MATS) prototype effectively concentrates diluted blood. This plasmapheresis-based system shows promise for autotransfusion applications.
Area of Science:
- Biomedical Engineering
- Medical Devices
Background:
- Autotransfusion is crucial for managing blood loss during surgery.
- Current autotransfusion devices have limitations in efficiency and patient comfort.
Purpose of the Study:
- To evaluate the performance of the first experimental prototype of the Membrane Autotransfusion System (MATS-I).
- To assess the system's ability to concentrate diluted blood for autotransfusion.
Main Methods:
- Utilized a specially designed polyethylene hollow fiber membrane.
- Tested the MATS-I prototype's blood concentration capabilities at a transmembrane pressure of 70 mm Hg.
- Evaluated continuous treatment of 10,000 ml of diluted blood at varying hematocrit levels.
Main Results:
- MATS-I successfully concentrated diluted blood from 10% to over 40% hematocrit.
- The system maintained performance during continuous treatment of large blood volumes.
- The prototype met essential autotransfusion performance requirements.
Conclusions:
- The MATS-I demonstrates effective blood concentration for autotransfusion.
- Identified areas for improvement leading to the development of the next prototype, MATS-II.
- MATS offers potential advantages over centrifugal autotransfusion devices, including smaller size, reduced trauma, and continuous operation.