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Diffuse annular fusiform adenocarcinoma in a dog
M R Prater1, B Flatland, S J Newman
1Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic and State University, Blacksburg 24061-0442, USA.
Journal of the American Animal Hospital Association
|March 24, 2000
Summary
A rare canine intestinal adenocarcinoma case involved diffuse infiltration of the entire large bowel in a German shepherd. Unique features included minimal desmoplasia and widespread metastasis, presenting diagnostic challenges for veterinary oncologists.
Area of Science:
- Veterinary Oncology
- Canine Pathology
- Gastrointestinal Neoplasia
Background:
- Canine colonic intestinal adenocarcinoma commonly presents as localized masses.
- Clinical signs often relate to obstructive large bowel disease.
Observation:
- An 11-year-old German shepherd presented with anorexia, diarrhea, and weight loss.
- Endoscopic biopsies and postmortem examination revealed diffuse infiltration of the entire large bowel by adenocarcinoma.
- The lesion was an unusual annular fusiform shape.
Findings:
- The canine intestinal adenocarcinoma showed a paucity of desmoplasia.
- Widespread metastasis was observed in regional lymph nodes, lung, and prostate.
- This presentation is atypical for canine colonic adenocarcinoma.
Implications:
- This case highlights the diverse presentations of canine intestinal adenocarcinoma.
- Understanding unusual patterns is crucial for accurate diagnosis and treatment.
- Further research into factors influencing desmoplasia and metastasis in canine cancer is warranted.