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Glottographic phase difference in recurrent nerve paralysis.

J Jiang1, E Lin, D G Hanson

  • 1Department of Otolaryngology-Head and Neck Surgery, Northwestern University School of Medicine, Chicago, Illinois 60611-3008, USA.

The Annals of Otology, Rhinology, and Laryngology
|March 29, 2000
PubMed
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This study shows that glottographic phase difference (GPD) effectively detects unilateral recurrent laryngeal nerve (RLN) paralysis in men. The GPD measure reliably distinguishes patients with RLN paralysis from healthy controls.

Area of Science:

  • Laryngology
  • Voice Disorders
  • Neurology

Background:

  • Recurrent laryngeal nerve (RLN) paralysis affects vocal fold vibration.
  • Simultaneous electroglottography (EGG) and photoglottography (PGG) have shown promise in canine models.
  • Clinical application of these phase measures requires further investigation.

Purpose of the Study:

  • To evaluate the clinical utility of glottographic phase difference (GPD) in diagnosing unilateral RLN paralysis.
  • To assess the effectiveness of combined EGG and PGG signals in identifying vocal fold dysfunction.

Main Methods:

  • Simultaneous EGG and PGG signals were recorded from 5 men with unilateral RLN paralysis and 5 age-matched controls.
  • A glottographic phase difference (GPD) measure was calculated from the combined signals.

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  • A validity analysis was performed on 19 subjects to confirm the GPD test's efficiency.

    • Main Results:

    • Patients with unilateral RLN paralysis exhibited a consistent phase delay between EGG and PGG waveforms.
    • The GPD measure significantly differed between the control group (0.2371 ms) and the patient group (-0.2765 ms).
    • The GPD test demonstrated high efficiency (91.7%) in detecting unilateral RLN paralysis in males.

    Conclusions:

    • Glottographic phase difference (GPD) is a valuable clinical tool for detecting unilateral RLN paralysis.
    • Combined EGG and PGG signal analysis offers a reliable method for assessing vocal fold vibration abnormalities.
    • The GPD test shows high diagnostic accuracy in the male population.