Related Experiment Video
Updated: Aug 6, 2026

Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
Published on: June 10, 2015
Insights
Hypertension, affecting over 50 million adults, is high blood pressure (≥140/90 mmHg). This condition significantly increases the risk for serious health issues like heart disease and stroke.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Hypertension, or high blood pressure, affects over 50 million adults in the U.S.
- Defined as systolic blood pressure (SBP) ≥140 mmHg and/or diastolic blood pressure (DBP) ≥90 mmHg, or use of antihypertensive medication.
- Hypertension is a major risk factor for cardiovascular and cerebrovascular diseases.
Purpose of the Study:
- To summarize the prevalence and health implications of hypertension in the U.S. adult population.
Main Methods:
- Data synthesis on hypertension prevalence.
- Review of established medical definitions for hypertension.
- Literature review on associated health conditions.
Main Results:
- Estimates indicate over 50 million U.S. adults have hypertension.
- Hypertension is directly linked to conditions such as coronary artery disease (CAD), renovascular disease, and cerebrovascular accidents.
Conclusions:
- Hypertension is a widespread public health concern in the U.S.
- Effective management of hypertension is crucial for preventing severe secondary health conditions.
Abstract:
More than 50 million U.S. adults are estimated to have hypertension--defined as systolic blood pressure (SBP) of at least 140 mmHg and/or diastolic blood pressure (DBP) of at least 90 mmHg--or take antihypertensive medication. Hypertension is directly implicated in a range of conditions, including coronary artery disease (CAD), renovascular disease, and cerebrovascular accidents.
Related Concept Videos
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension IV: Drug Therapy and Lifestyle Modifications
Hypertension V: Nursing Management

