Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Current data on the extrarenal renin-angiotensin system].

I Haulică1, G Petrescu, S Slătineanu

  • 1Disciplina de Fiziologie, Facultatea de Medicină, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.

Revista Medico-Chirurgicala a Societatii De Medici Si Naturalisti Din Iasi
|April 11, 2000
PubMed
Summary

The study explores the renin-angiotensin system (RAS), detailing both renal and extrarenal components. It highlights how circulating and tissue RAS cooperate to maintain bodily functions and homeostasis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CENTRAL AND PERIPHERAL EFFECT OF MPTP VIA DOSE-DEPENDENT MAGNESIUM MODULATION.

Acta endocrinologica (Bucharest, Romania : 2005)·2023
Same author

[New parameters of electrocardiotachographic (EKT) evaluation of the organovegetative reactivity].

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2015
Same author

Interactions between the oxidative and nitrosative stress in nociceptive processing in rat.

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2013
Same author

Ghrelin and Ang 1-7 have cumulative vasodilatory effects on pulmonary vessels.

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2011
Same author

Antioxidant activity in rat models of nociceptive stress.

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2010
Same author

Biosynthesis and physio-pharmacological actions of angiotensin peptides: 1. Synthetic enzymes.

Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi·2009

Area of Science:

  • Physiology
  • Endocrinology
  • Biochemistry

Context:

  • The renin-angiotensin system (RAS) plays a crucial role in regulating blood pressure and fluid balance.
  • While the renal component of RAS is well-studied, extrarenal and tissue-specific RAS require further elucidation.
  • Understanding the interplay between different RAS components is vital for comprehending overall physiological regulation.

Purpose:

  • To review the primary extrarenal angiotensin-forming enzymes.
  • To present data on tissue RAS distribution in various organs including the heart, brain, and glands.
  • To elucidate the relationship and cooperative function between circulating and tissue RAS.

Summary:

  • This review details extrarenal angiotensin-forming enzymes (isorenin, tonin, cathepsin D & G, conversion enzyme, chymase).

Related Experiment Videos

  • It examines tissue RAS in the heart, vessels, brain, accessory glands, adrenal cortex, and gonads.
  • The study emphasizes the cooperative interaction between renal and extrarenal RAS, forming a unified hormonal system for homeostasis.

    • Impact:

    • Highlights the dual role of RAS in short-term (circulating) and long-term (tissue) homeostatic regulation.
    • Provides a comprehensive overview of tissue-specific RAS, aiding in understanding localized physiological adaptations.
    • Underscores the integrated nature of the RAS, crucial for maintaining overall organismal function and equilibrium.