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Updated: Aug 16, 2026

Characterization of MLKL-mediated Plasma Membrane Rupture in Necroptosis
Published on: August 7, 2018
Abstract:
Necrotizing fasciitis is a progressive destructive infection in the subcutaneous tissue. It represents a serious problem in medicine both in making the correct early diagnosis and in treatment. We describe the symptoms, the clinical and paraclinical findings and the guidelines for treatment. Nine cases of necrotizing fasciitis are reported schematically, three cases are presented in text. Only two patients survived, one of these received intravenous immunoglobulin. Of the seven dead, five received intravenous immunoglobulin.
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