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Hopkins Lupus Cohort. 1999 update
1Hopkins Lupus Cohort, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. mpetri@welchlink.welch.jhu.edu
Rheumatic Diseases Clinics of North America
|April 18, 2000
Summary
This study reviews predictors of disease activity, damage, and health status in 800 patients with systemic lupus erythematosus (SLE) from the Hopkins Lupus Cohort. Findings help understand and manage SLE progression and patient well-being.
Area of Science:
- Rheumatology
- Immunology
- Clinical Medicine
Background:
- The Hopkins Lupus Cohort is a prospective, decade-long study.
- It includes 800 patients diagnosed with systemic lupus erythematosus (SLE).
Purpose of the Study:
- To review predictors of disease activity in SLE patients.
- To identify factors contributing to disease damage, including accelerated atherosclerosis and antiphospholipid antibody syndrome.
- To examine predictors of health status in individuals with SLE.
Main Methods:
- Prospective cohort study design.
- Review of data from 800 SLE patients over a decade.
- Analysis of disease activity, damage, and health status metrics.
Main Results:
- Identification of key predictors for SLE disease activity.
- Understanding factors leading to severe SLE complications like atherosclerosis and antiphospholipid antibody syndrome.
- Insights into determinants of health status among SLE patients.
Conclusions:
- Predictors of disease activity, damage, and health status in SLE are crucial for patient management.
- The Hopkins Lupus Cohort provides valuable data for understanding SLE.
- Further research can leverage these findings to improve patient outcomes and quality of life.