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Tilting disc versus bileaflet aortic valve substitutes: intraoperative and postoperative hemodynamic performance in
P Kleine1, M J Hasenkam, H Nygaard
1Department of Cardiothoracic Surgery, Herz-Kreislauf-Klinik Bevensen, Bad Bevensen, Germany.
Background And Aim Of The Study:
Due to an asymmetrical/eccentric flow profile at the level of the aortic valve, there is an optimal orientation for each aortic valve design. This study evaluates intraoperative flow dynamics (turbulence and pressure gradient) and follow up results (pressure gradient and left ventricular mass regression) for Medtronic Hall tilting disc (MH) and St. Jude Medical bileaflet (SJM) valves, with both valves in their optimum orientation as defined in previous animal experiments.
Methods:
In a randomized prospective study, MH and SJM valves (size > or = 23 mm) were implanted in their optimum orientation in 24 patients with aortic stenosis. Turbulence measurements were performed intraoperatively via a perivascular ultrasound transducer; Reynold's normal stress (RNS) values were calculated as key markers for turbulent stresses. Transvalvular pressure gradients, interventricular septum and posterior wall thickness were measured by transesophageal echocardiography intraoperatively and six months postoperatively.
Results:
Mean valve size was 23.8 mm in both groups. Intraoperative RNS values (MH 7.5 +/- 2.2 N/m2 versus SJM 9.8 +/- 2.3 N/m2) and pressure gradients (MH 10.0 +/- 2.6 mmHg versus SJM 20.0 +/- 3.4 mmHg) were significantly lower for the tilting disc valve. At six months follow up, pressure gradients were reduced by half for both valves (MH 5.3 +/- 1.7 mmHg; SJM 10.4 +/- 2.3 mmHg), with the difference between the valves being maintained. Left ventricular mass regression was accelerated for MH patients with regard to interventricular septum thickness.
Conclusion:
Our results indicate that the tilting disc mechanism shows superior hemodynamic performance with respect to turbulence and transvalvular pressure gradients compared with the bileaflet mechanism when both valves are implanted in their optimum orientation. This led to significant acceleration of interventricular septum mass regression. The superiority of the tilting disc mechanism is more pronounced in the smaller-sized valves.