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Synthesis and antimicrobial activity of 1,4-diaryl-2-azetidinones
V Güner1, S Yildirir, B Ozçelik
1Department of Chemistry, Faculty of Science, Hacettepe University, Ankara, Turkey.
Farmaco (Societa Chimica Italiana : 1989)
|April 27, 2000
Abstract:
Cycloaddition of substituted 4,4-benzylidene-anilines to in situ prepared dichloroketenes in the presence of dichloroacetyl chloride and triethylamine affords a variety of 2-azetidinones. All the compounds were characterized by IR and 1H NMR. Their antimicrobial activity, against Gram(+) and Gram(-) bacteria and fungi, was tested.