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Published on: June 21, 2019
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[Neuroendocrine carcinoma: first case observed in Dakar]
M T Dieng1, B Ndiaye, E Grosshans
1Service de Dermatologie Hopital A. Le Dantec, Dakar Sénégal.
Dakar Medical
|May 8, 2000
Summary
This is the first reported case of Merkel cell carcinoma in Dakar, a rare skin cancer. The unusual presentation in a young Black woman highlights the need for broader diagnostic considerations.
Area of Science:
- Oncology
- Dermatology
- Pathology
Background:
- Neuroendocrine carcinoma, specifically Merkel cell carcinoma (MCC), is a rare and aggressive skin cancer.
- MCC typically affects elderly Caucasians, predominantly on the head and neck.
- This report details the first documented case of MCC in Dakar, Senegal.
Observation:
- A 21-year-old Black female presented with three nodular lesions on her left foot.
- Lesions appeared 8 months prior to presentation.
- Enlarged inguinal and popliteal lymph nodes were noted.
Findings:
- Histopathology and immunocytochemistry confirmed Merkel cell carcinoma.
- The patient's young age, Black race, and tumor location on the foot were atypical for MCC.
- Early lymph node and pulmonary metastases were observed.
Implications:
- This case expands the known demographic and clinical spectrum of Merkel cell carcinoma.
- Highlights the importance of considering MCC in young individuals and diverse populations, even with unusual tumor sites.
- Emphasizes the aggressive nature and potential for early metastasis in atypical MCC presentations.
