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Benzhydryldimethylsilyl allylic silanes: syntheses and applications to
1Department of Chemistry, University of California, Irvine, California 92697-2025, USA.
Abstract:
A new silyl group, the benzhydryldimethylsilyl group, has been developed that is easily synthesized and that undergoes facile oxidation. The [3 + 2] annulation reactions of allylic silanes with this silyl group provide a variety of highly substituted five-membered carbocycles and heterocycles with high stereoselectivities. The silyl groups of these cyclic compounds have been oxidized to hydroxyl groups to demonstrate the general synthetic utility of the method.
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