Local, passive transfer of purified protein derivative-delayed tuberculin hypersensitivity by guinea pig...

Delayed skin reactions to purified protein derivative could be produced in guinea pigs by passive transfer of the population of sensitized lymphocytes, which have the ability to form rosettes with rabbit erythrocytes. Because it has been shown earlier that guinea pig thymus-dependent lymphocytes rosette with rabbit erythrocytes, it is concluded that thymus-dependent lymphocytes mediate delayed type hypersensitivity.