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Related Experiment Videos

Allergic contact dermatitis to gold.

A Ehrlich1, D V Belsito

  • 1Department of Medicine, University of Kansas Medical Center, Kansas City 66160-7319, USA.

Cutis
|May 29, 2000
PubMed
Summary
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Gold allergy is a common cause of contact dermatitis, particularly on the face and eyelids. Discontinuing gold jewelry contact cleared dermatitis in nearly half of allergic patients, with some needing to avoid other allergens too.

Area of Science:

  • Allergy and Immunology
  • Dermatology
  • Contact Dermatitis

Background:

  • Gold is a frequent contact allergen.
  • Gold allergy can manifest as dermatitis on the face, eyelids, and direct contact sites.

Purpose of the Study:

  • To evaluate the prevalence of gold allergy in patients with suspected contact dermatitis.
  • To assess the effectiveness of discontinuing gold contact in managing gold-allergic contact dermatitis.

Main Methods:

  • Patch testing was performed on 355 patients with suspected contact dermatitis.
  • Seventeen patients (4.8%) were identified as gold-allergic.
  • Follow-up re-evaluation of 15 gold-allergic patients after discontinuing gold contact.

Main Results:

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  • Nearly half (46.7%) of gold-allergic patients experienced dermatitis clearance upon avoiding gold jewelry.
  • Some patients required avoidance of additional allergens for symptom resolution.
  • Complete symptom clearing occurred in 46.7% of patients even with continued gold exposure, by avoiding other allergens.

Conclusions:

  • Gold allergy is a significant cause of contact dermatitis.
  • Avoiding gold jewelry is an effective management strategy for gold-allergic contact dermatitis.
  • Management may require a comprehensive approach including avoidance of other allergens.