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Updated: Jul 29, 2026

Transformation of Probiotic Yeast and Their Recovery from Gastrointestinal Immune Tissues Following Oral Gavage in Mice
Published on: February 8, 2016
[The effect of yeast glycans in experimental LPS-induced endotoxicosis]
1Chemico-Pharmaceutical Academy, St. Petersburg, Russia.
Abstract:
The immunomodulating action of yeast glycans obtained from Rhodotorula rubra (rhonasan) and Sporobolomyces albo-rubescens (heteroglycan Sp-50) was studied under the conditions of experimental endotoxicosis in mice, induced by the injection of the sublethal dose of Escherichia coli lipopolysaccharide (LPS). In endotoxicosis glycans produced a protective effect, depending on the time of injection. The study demonstrated that after the injection of glycans the survival rate of the animals increased and the LPS-inhibited function of peritoneal macrophages and B lymphocytes was completely or partially restored.
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