Related Experiment Videos
Cat scratch disease in 2 siblings presenting as acute gastroenteritis
G Liapi-Adamidou1, M Tsolia, A M Magiakou
1Second Department of Pediatrics, University of Athens School of Medicine, P. and A. Kyriakou Children's Hospital, Greece.
Insights
Cat scratch disease can mimic gastroenteritis. This study highlights its varied presentations, including rare complications like bone lesions, emphasizing the need for broader recognition in pediatric cases.
Area of Science:
- Infectious Diseases
- Pediatrics
- Microbiology
Background:
- Cat scratch disease (CSD) is a bacterial infection caused by Bartonella henselae.
- It is typically transmitted through cat scratches or bites.
- Clinical manifestations of CSD are diverse and can be challenging to diagnose.
Observation:
- Two siblings presented with symptoms initially suggestive of acute febrile gastroenteritis.
- The elder sibling developed mesenteric lymphadenitis, hepatosplenic granulomas, and osteolytic bone lesions.
- The younger sibling experienced a milder, self-limited illness without complications.
Findings:
- CSD can present with gastrointestinal symptoms, mimicking other common pediatric illnesses.
- Protracted CSD cases may lead to severe systemic complications, including bone involvement.
- Disease severity and clinical course can vary significantly between individuals, even within the same family.
Implications:
- Early recognition of CSD is crucial to prevent severe outcomes.
- Physicians should consider CSD in the differential diagnosis of pediatric febrile illnesses with gastrointestinal symptoms.
- Further research is needed to fully understand the spectrum of CSD manifestations and optimize diagnostic strategies.
Abstract:
The cases of 2 siblings with cat scratch disease are described who presented with symptoms suggestive of acute febrile gastroenteritis. The first patient, a 7.5-y-old girl, developed mesenteric lymphadenitis, hepatosplenic granulomas and osteolytic bone lesions only late in the course of her protracted illness. Her 3-y-old brother had a shorter, self-limited illness without complications. Cat scratch disease is often unrecognized and the full spectrum of its clinical manifestations remains to be investigated.