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Updated: Aug 16, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Transcranial-transdural real-time ultrasonography during transsphenoidal resection of a large pituitary tumor. Case
J L Atkinson1, J L Kasperbauer, E M James
1Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, 55905, USA. atkinson.john@mayo.edu
Abstract:
Ultrasonography has been used in neurosurgical operative procedures for several decades. The authors report the case of a large pituitary tumor that was subtotally resected using endoscopy via the transnasal-transsphenoidal approach, with the aid of transcranial real-time ultrasound. To our knowledge, this is the first reported case in which intraoperative transcranial-transdural real-time ultrasound was used to facilitate the resection of a skull base tumor.

