Particles released from the Gyro C1E3 during simulated extracorporeal circulation

Area of Science:

• Biomedical Engineering
• Medical Devices
• Cardiovascular Technology

Background:

• Microembolism is a risk during extracorporeal circulation.
• Released particles from blood pumps can cause microembolism.
• Evaluating particle release is crucial for blood pump safety.

Purpose of the Study:

• To evaluate particle release from the Gyro C1E3 centrifugal blood pump.
• To compare particle release between the Gyro C1E3 and a roller pump.
• To assess the risk of microembolism associated with the Gyro C1E3.

Main Methods:

• The Gyro C1E3 was operated for 14 days simulating left ventricular assist device (LVAD) and percutaneous cardiopulmonary support (PCPS).
• A roller pump was operated for 2 days for comparison.
• Released particles were collected, weighed, and analyzed using Scanning Electron Microscopy (SEM).

Main Results:

• After 14 days, the Gyro C1E3 released 238.6 microg of particles under LVAD conditions.
• The roller pump released 270.2 microg of particles in just 2 days.
• Average particle size was 0.6 microm for the C1E3 versus 3.7 microm for the roller pump.

Conclusions:

• The Gyro C1E3 demonstrates a substantially lower risk of microembolism due to reduced particle release.
• The centrifugal design of the Gyro C1E3 appears advantageous in minimizing particle generation.
• Further evaluation supports the Gyro C1E3 as a safer option for extracorporeal circulation support.