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Updated: Aug 11, 2026

A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
Published on: June 8, 2014
[Physical activity, bone remodeling, and osteoporosis]
Abstract:
Scientific publications have produced debate about the action of the physical activity in the osteoporosis. It's condition by several factors, like the repercussion of the physical activity in the bone remodeling, the loss of bone mass with immobilization or the gravitational effect. The progressive knowledge of the different nutritional and direct and indirect biochemical factors that stimulates, inhibits or modulates the bone remodeling, and the new methodology in the evaluation of the bone mineral density and the biomarkers of bone resorption or bone formation have confirmed or denied the results apparently contradictory. We analyse the advantages of the action of the physical activity in the normal bone remodeling process, his risk factors in some deportive actions. The not confirmation of the therapeutic utility of the physical activity in the osteoporosis, and the actual research about the amount of bone that can be gained by activity or high bone mass in a determined age, with special emphasis in the activity for tension of muscular contraction and the percussion effect for the specific sport action.
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