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Commitment factors for T helper cells
1Division of Immunology, DNAX Research Institute of Molecular and Cellular Biology, Palo Alto, CA 94304-1104, USA.
Current Biology : CB
|July 19, 2000
Abstract:
Cytokines are dominant factors in driving the development of T helper cell subsets via specific signaling pathways. Transcription factors specific to the T helper cell lineages have also been shown to determine the commitment of Th1 and Th2 cells to the production of distinct profiles of cytokines.