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Isolation and Culture of Mouse Cortical Astrocytes
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Isolation and Culture of Mouse Cortical Astrocytes

Published on: January 19, 2013

Effect of dexamethasone on nitric oxide (NO.) production by cultured astrocytes

S Lavista Llanos1, A Roldán

  • 1Instituto de Biología y Medicina Experimental, Buenos Aires, Argentina.

Biocell : Official Journal of the Sociedades Latinoamericanas De Microscopia Electronica ... Et. Al
|July 25, 2000
PubMed

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Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure to...