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[Severe Raynaud's phenomenon associated with interferon-beta therapy for multiple sclerosis: case report]
B A Cruz1, E D Queiroz, S V Nunes
1Faculdade de Medicina, Universidade Federal de Minas Gerais. borisc@net.cm.com.br
Abstract:
Interferon-beta (IFN-beta) is administered for treatment of multiple sclerosis (MS). We report on a woman with MS who presented with severe Raynaud's phenomenon, livedo-reticularis and digital necrosis two weeks after beginning therapy with IFN-beta. Symptoms improved after the IFN-beta was discontinued and anticoagulation associated with cyclophosphamide and corticoid were introduced. Raynaud's phenomenon is probably a side effect of IFN-beta therapy for multiple sclerosis.
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