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Published on: January 18, 2011
[Direct modulatory effects of G proteins on voltage-dependent ion channels of nerve cells]
Abstract:
Neurotransmitters have regulative effects on voltage-dependent ion channels of nerve cells. Recent studies have shown that voltage-dependent channels were modulated by transmitters through direct interactions between G proteins and channels without any known second messengers being involved. This gave us a novel understanding of the relations between G proteins and voltage-dependent ion channels. This article reviews the phenomena, characteristics, and mechanisms about voltage-dependent channels modulated by transmitters through direct effects of G proteins.
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