Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Osteonecrosis.

K Pavelka1

  • 1Institute of Rheumatology, Charles University, Prague, Czech Republic.

Bailliere'S Best Practice & Research. Clinical Rheumatology
|August 5, 2000
PubMed
Summary
This summary is machine-generated.

Osteonecrosis, or bone death, results from various conditions and commonly affects the femoral head. Early diagnosis and intervention significantly improve patient outcomes, though hip replacement remains frequent.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Drug survival analysis of etanercept compared with monoclonal antibody tumour necrosis factor-α inhibitors in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: a propensity score-matched analysis from the Czech ATTRA registry.

Scandinavian journal of rheumatology·2024
Same author

IL-40 is up-regulated in the synovial fluid and cartilage of osteoarthritis patients and contributes to the alteration of chondrocytes phenotype in vitro.

Arthritis research & therapy·2024
Same author

Serum biomarkers and their relationship to axial spondyloarthritis associated with inflammatory bowel diseases.

Autoimmunity reviews·2024
Same author

Circulating miRNAs in hand osteoarthritis.

Osteoarthritis and cartilage·2022
Same author

A decrease in serum 1,25(OH)<sub>2</sub>D after elective hip replacement and during bone healing is associated with changes in serum iron and plasma FGF23.

Journal of endocrinological investigation·2022
Same author

Circulating miR-145 as a marker of therapeutic response to anti-TNF therapy in patients with ankylosing spondylitis.

Physiological research·2021
Same journal

Preface

Bailliere's best practice & research. Clinical rheumatology·2000
Same journal

Index

Bailliere's best practice & research. Clinical rheumatology·2000
Same journal

How do we manage chronic pain?

Bailliere's best practice & research. Clinical rheumatology·2000
Same journal

The biopsychosocial model--a tool for rheumatologists.

Bailliere's best practice & research. Clinical rheumatology·2000
Same journal

The psychology of rheumatic diseases.

Bailliere's best practice & research. Clinical rheumatology·2000
Same journal

Physical therapy and rehabilitation in the management of rheumatic disorders.

Bailliere's best practice & research. Clinical rheumatology·2000
See all related articles

Area of Science:

  • Orthopedics
  • Radiology
  • Pathology

Background:

  • Osteonecrosis (avascular necrosis) is a bone death pathway, not a distinct disease.
  • Key risk factors include trauma, glucocorticosteroids, alcoholism, and connective tissue disorders.
  • Idiopathic cases also occur, with common sites being the femoral head, humeral head, knee, and small bones.

Purpose of the Study:

  • Focus on high-risk patients for osteonecrosis.
  • Emphasize evidence-based diagnosis, particularly for early stages.
  • Detail evidence-based treatment aligned with osteonecrosis staging.

Main Methods:

  • Review of predisposing factors for osteonecrosis.
  • Evaluation of advanced imaging techniques like MRI for early detection.

Related Experiment Videos

  • Analysis of factors influencing patient outcomes, including size and location of necrosis.

    • Main Results:

    • Magnetic resonance imaging (MRI) enhances early osteonecrosis diagnosis when radiographs are normal.
    • Patient outcomes depend on necrosis size and location.
    • Early interventions improve outcomes, but nearly 50% of femoral head osteonecrosis cases require arthroplasty.

    Conclusions:

    • Early diagnosis and intervention are crucial for managing osteonecrosis.
    • Tailoring treatment to the stage of osteonecrosis is essential.
    • Despite advances, femoral head osteonecrosis frequently necessitates hip replacement surgery.