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Recurrent Caffey's cortical hyperostosis and persistent deformity.

E Blank

    Pediatrics
    |June 1, 1975
    PubMed
    Summary
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    Caffey's disease, or infantile cortical hyperostosis, can recur in children and young adults, causing bone thickening and pain. Persistent symptoms may indicate late-onset or recurrent Caffey's disease.

    Area of Science:

    • Pediatric Orthopedics
    • Medical Genetics

    Background:

    • Infantile cortical hyperostosis (Caffey's disease) is a rare disorder.
    • Typically presents in infancy with bone swelling, fever, and irritability.

    Observation:

    • A 12-year-old boy with a history of infantile cortical hyperostosis experienced recurrent bone pain and new cortical thickenings.
    • The patient also exhibited mandibular undergrowth and abnormal rib slope.

    Findings:

    • This case highlights the potential for recurrence of Caffey's disease beyond infancy.
    • Persistent symptoms and late-onset cortical thickening may be manifestations of recurrent or atypical Caffey's disease.

    Implications:

    • Suggests that Caffey's disease may have a broader clinical spectrum and longer-term implications than previously recognized.

    Related Experiment Videos

  • Highlights the importance of considering recurrent Caffey's disease in the differential diagnosis of unexplained bone pain and cortical thickening in children and young adults.