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[Depression in older persons].

M Cvjetković-Bosnjak1, A Knezević, B Soldatović-Stajić

  • 1Institut za neurologiju, psihijatriju i mentalno zdravlje, Klinicki centar, Novi Sad Medicinski fakultet, Novi Sad.

Medicinski Pregled
|August 31, 2000
PubMed
Summary

Older adults with depression experienced quicker symptom remission with moclobemide compared to mianserin. Adequate therapy is key for resolving depressive symptoms in elderly patients.

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Area of Science:

  • Geriatric psychiatry
  • Clinical psychology
  • Neuroscience

Context:

  • Depression is prevalent in older adults, often exacerbated by medical conditions and life losses.
  • Elderly individuals face significant risks, including high suicide rates, with depression being a major contributing factor.
  • Effective treatment aims to alleviate symptoms, prevent recurrence, enhance quality of life, and reduce mortality in geriatric depression.

Purpose:

  • To compare the efficacy of moclobemide and mianserin in treating depressive disorders in elderly female inpatients.
  • To evaluate the speed of depressive symptom remission in older patients receiving different pharmacological treatments.

Summary:

  • This study examined 32 female inpatients diagnosed with middle depressive disorder (ICD-X), excluding those with cognitive impairment (Mini-Mental State Examination).
  • The Hamilton Rating Scale for Depression was used for weekly efficacy evaluations.
  • Results indicated that patients treated with moclobemide achieved faster remission of depressive symptoms than those treated with mianserin.

Impact:

  • Moclobemide demonstrates a potential advantage in rapidly alleviating depressive symptoms in older adults.
  • Findings underscore the importance of timely and appropriate pharmacological interventions for geriatric depression.
  • This research contributes to optimizing treatment strategies for depression in the elderly population.

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