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Peculiarities of cardiotropic effect of aconitine
Y R Sheikh-Zade1, I L Cherednik, P A Galenko-Yaroshevskii
1Department of Normal Physiology, Kuban Medical Academy, Krasnodar.
Bulletin of Experimental Biology and Medicine
|September 8, 2000
Abstract:
In experiments on anesthetized cats, aconitine produced direct arrhythmogenic and cardiotoxic effects on the myocardium combined with indirect cardiotropic effects mediated via activation of extracardial nerves. Aconitine demonstrated pronounced cholinolytic properties and blocked vagal arrhythmogenic effect.