[Immunological disorders in patients with uterine myomas]

The investigations covered a group of 20 patients with uterine myomas aged 38 to 57 years. The control group consisted of 20 healthy women. The following indices were used in the assessment of non-specific immunity: 1) determination of the total leukocyte number and neutrophil number in peripheral blood, 2) the investigation of NBT reduction by neutrophils, 3) the evaluation of myeloperoxidase activity in neutrophils. 4) the assessment of alkaline phosphatase activity in neutrophils, 5) the evaluation of the neutrophil adherence ability, 6) determination of phagocytic activity of neutrophils, 7) determination of lysozyme activity in serum, 8) the evaluation of concentration of immune complexes in serum. In the group of patients with myomas the following indices were found as a statistically significant: a) the increase of leukocyte and neutrophil number b) the increase of the index of stimulated reduction of NBT, c) the decrease of myeloperoxidase activity, d) the increase of activity of alkaline phosphatase in neutrophils, e) the increase of the index of adherence, f) the decrease of the phagocytic activity.