[Comparison study of some neutrophils indices in neonates and adults]

The purpose of this study was to estimate the difference in a range of number values, function and metabolism of neutrophil granulocyte sampled from umbilical cord of healthy and full-term newborns and healthy adults. The following indices were measured: total neutrophils number, neutrophil adherence to fibre, nitrobluetetrazolium reduction ability, phagocytic activity, alkaline phosphatase activity and lysozyme activity in serum. Results of the study showed that neutrophils from healthy newborns, when compared with neutrophils from adults, demonstrated the increase of oxidation-reduction processes, the increase of alkaline phosphatase activity in these cells and lysozyme activity in serum. It was associated with the increase of count of neutrophils what resulted from the decrease of their adherence.