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Related Experiment Videos

Fibromyalgia, hypermobility, and breast implants.

S Lai1, J A Goldman, A H Child

  • 1Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD, USA.

The Journal of Rheumatology
|September 16, 2000
PubMed
Summary

Hypermobility is linked to both fibromyalgia and breast implants, but fibromyalgia and breast implants are not directly associated. This study investigated these connections in 2,500 women.

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Area of Science:

  • Rheumatology
  • Connective Tissue Diseases
  • Surgical Implants

Background:

  • Fibromyalgia (FM) is a chronic pain disorder.
  • Hypermobility, a condition involving excessive joint flexibility, is common in some rheumatic diseases.
  • Breast implants are widely used cosmetic and reconstructive devices.

Purpose of the Study:

  • To investigate the potential associations between fibromyalgia (FM), hypermobility, and breast implants.
  • To determine if breast implantation precedes or is associated with the development of FM.
  • To explore the independent relationships among these three conditions.

Main Methods:

  • Retrospective analysis of 2,500 female patients' medical records (ages 25-65) in a rheumatology practice.
  • Comparison of patients meeting FM criteria versus those who did not.

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  • Statistical analysis including univariate and multivariate regression, adjusting for age, income, and other rheumatic conditions.

    • Main Results:

    • Hypermobility showed a significant association with fibromyalgia (adjusted OR 2.20).
    • Hypermobility was also significantly associated with breast implantation (adjusted OR 1.80).
    • No significant association was found between breast implantation and subsequent development of fibromyalgia (adjusted OR 0.74).

    Conclusions:

    • Hypermobility is independently associated with both fibromyalgia and breast implantation.
    • There is no independent association found between breast implantation and fibromyalgia.
    • These findings suggest hypermobility as a potential shared factor or confounder in studies examining FM and breast implants.