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Related Experiment Videos

Virginal breast hypertrophy.

P M O'Hare1, I J Frieden

  • 1Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Pediatric Dermatology
|September 16, 2000
PubMed
Summary
This summary is machine-generated.

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Virginal breast hypertrophy, a rare condition causing rapid breast enlargement in puberty, presents unique dermatologic challenges. Dermatologists should recognize associated skin changes and manage them until surgical intervention is possible.

Area of Science:

  • Dermatology
  • Endocrinology
  • Pediatric Surgery

Background:

  • Macromastia involves massive breast enlargement disproportionate to body growth.
  • Virginal breast hypertrophy is a rare, distinct disorder characterized by rapid macromastia onset at puberty.
  • This condition is seldom reported in dermatologic literature.

Observation:

  • Two cases of virginal breast hypertrophy are presented.
  • Case 1: A 14-year-old girl with macromastia post-liver transplant, exhibiting erythema and verrucous hyperplasia.
  • Case 2: A 12-year-old girl with severe bilateral breast enlargement post-thyrotoxicosis treatment, experiencing tenderness, erythema, and edema.

Findings:

  • Virginal breast hypertrophy can manifest with significant cutaneous changes, including erythema, edema, and hyperplasia.

Related Experiment Videos

  • Tamoxifen citrate showed symptomatic improvement in one patient with virginal breast hypertrophy.
  • Dermatologists may encounter and need to manage skin manifestations associated with this condition.

    • Implications:

    • Dermatologists should be aware of virginal breast hypertrophy due to potential skin involvement.
    • Management of cutaneous manifestations is crucial while awaiting stabilization of breast growth for definitive surgical therapy.
    • Early recognition and dermatologic consultation can improve patient outcomes for virginal breast hypertrophy.