A novel scheme for the selective stimulation of nerve fibers using nonlinear properties of action potentials

In this paper, we propose a novel technique for selective stimulation of nerve fibers. We show that a set of point electrodes arranged in the 3-D space around a nerve trunk can be used to systematically synthesize highly useful activation patterns within the nerve, by exploiting the spatial arrangement of the electrodes and the excitation currents. Using such activation patterns, we present a novel scheme to selectively stimulate nerve fibers, based on the nonlinear properties of action potential generation. We illustrate the developed techniques via computer simulations of a nerve trunk consisting of a large number of nerve fibers. The results indicate that the proposed technique has great potential to achieve position selective stimulation of nerve in FES.