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Spasmolytic constituents from Eucalyptus camaldulensis var. obtusa leaves
1H. E. J. Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan. sabira@khi.comsats.net.pk
Journal of Natural Products
|September 23, 2000
Abstract:
Phytochemical studies on the leaves of Eucalyptus camaldulensis var. obtusa have resulted in the isolation of a new triterpenoid camaldulin (3beta-formyloxyurs-11-en-28,13beta-olide) (1) along with ursolic acid lactone acetate (2), ursolic acid lactone (3), betulinic acid (4), and beta-sitosterol 3-O-beta-D-glucopyranoside (5). The structures were assigned on the basis of 1D and 2D NMR studies. Compounds 1-3 were tested for spasmolytic activity and were found to possess calcium antagonist activity.