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Updated: Aug 8, 2026

Two Methods for Establishing Primary Human Endometrial Stromal Cells from Hysterectomy Specimens
Published on: May 23, 2014
Low-grade endometrial stromal sarcoma of the ectocervix after therapy for breast cancer
C H Boardman1, M J Webb, J A Jefferies
1Department of Obstetrics and Gynecology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.
Objective:
Low-grade endometrial stromal sarcoma is an uncommon, indolent uterine sarcoma that can arise in extrauterine locations. The objective of this study was to report on a previously unpublished site of origin for a low-grade endometrial stromal sarcoma.
Methods:
A case of a low-grade endometrial stromal sarcoma arising in the ectocervix after goserelin hormonal therapy for breast cancer was studied.
Results:
Low-grade endometrial stromal sarcoma can arise in the ectocervix even in the absence of endometriosis.
Conclusion:
Low-grade endometrial stromal sarcoma should be included in the differential diagnosis of sarcomas of the ectocervix.

