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Identification of a new HLA-B*78 allele in a Hispanic family
L Gaidulis1, P Krausa, B Schaub
1Department of Hematology/Bone Marrow Transplantation, City of Hope Medical Center, Duarte, California, USA.
Tissue Antigens
|October 6, 2000
Abstract:
A new B*78 variant, B*7804, was detected in three members of a Hispanic family. The novel B*78 sequence differs from B*78021 by two substitutions: T at nucleotide 527 (all other B*78s have A) and T at nucleotide 583 (all other B*78s have a C). Both nucleotide substitutions encode amino acid changes at codons 152 and 171, respectively.