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Published on: October 24, 2016
Multiple endocrine neoplasia in a dog
M Kiupel1, P B Mueller, J Ramos Vara
1Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, IN 47907, USA.
Abstract:
Multiple endocrine neoplasms, including an insulinoma, bilateral adrenocortical adenocarcinomas and an aortic paraganglioma, were diagnosed after euthanasia in a 12-year-old spayed female dog of mixed breed with a history of progressive anorexia, vomiting, diarrhoea, weight loss, polyuria and polydipsia, regenerative anaemia and hypoglycaemia. The clinical, gross pathological, microscopical, immunohistochemical and ultrastructural findings were consistent with the human syndrome of multiple endocrine neoplasia.
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