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Convenient preparation of 1-amidoindenes
A R Katritzky1, O V Denisko, S Busont
1Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu
The Journal of Organic Chemistry
|November 14, 2000
Abstract:
Lewis acid-catalyzed alpha-amidoalkylation of enolizable aldehydes with N-(alpha-benzotriazolyl-alpha-arylalkyl)amides followed by intramolecular Friedel-Crafts cyclization provides a convenient route to 2-substituted 1-amidoindenes.