Related Experiment Videos
[Corneal epithelial disturbance during topical use of latanoprost]
A Komuro1, N Yokoi, S Kinoshita
1Department of Ophthalmology, Kyoto Prefectural University of Medicine, Japan.
Purpose:
To report two cases with corneal epithelial disturbance during topical use of the new prostaglandin F 2 alpha derivative latanoprost and a beta-blocker.
Cases:
Both case 1 (82-year-old male) and case 2 (50-year-old female) were treated with topical antiglaucoma drugs for ocular hypertension.
Findings:
One month (case 1) and 10 days (case 2) after treatment with topical beta-blocker and latanoprost, corneal epithelial disturbance occurred. The corneal epithelial disturbance improved over several weeks with the preservative-free artificial tears after discontinuation of latanoprost and the beta-blocker.
Conclusion:
Careful observation is necessary during the course of treatment with latanoprost and a beta-blocker.