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Related Experiment Videos

Selenosis.

M F Raisbeck1

  • 1Department of Veterinary Sciences, College of Agriculture, University of Wyoming, Laramie, USA.

The Veterinary Clinics of North America. Food Animal Practice
|November 21, 2000
PubMed
Summary
This summary is machine-generated.

Selenium (Se) toxicity, or selenosis, affects animal health, impacting cardiovascular and gastrointestinal systems. Chronic effects include hair/hoof loss, immune, and reproductive damage, necessitating environmental assessment.

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Area of Science:

  • Veterinary Toxicology
  • Animal Nutrition
  • Environmental Health

Background:

  • Selenosis, a condition caused by selenium toxicity, has been studied for over six decades.
  • Certain aspects of its natural history and clinical presentation remain unclear in contemporary literature.
  • Understanding the diverse effects of selenium is crucial for animal health and agricultural productivity.

Purpose of the Study:

  • To clarify the natural history and clinical manifestations of acute and chronic selenosis in food animal species.
  • To differentiate historical descriptions of selenium toxicity from modern observations.
  • To highlight the economically significant impacts of chronic selenium exposure.

Main Methods:

  • Review of existing literature on selenium toxicity in food animals.

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  • Analysis of clinical signs associated with acute and chronic selenosis.
  • Comparison of historical accounts (e.g., "blind staggers") with current understanding of neurological lesions.

    • Main Results:

    • Acute selenium toxicity primarily targets cardiovascular, gastrointestinal, and hematopoietic systems in food animals.
    • Swine can exhibit neurological lesions, distinct from historical "blind staggers" descriptions.
    • Chronic selenosis is characterized by hair and hoof loss, with significant, though less specific, impacts on immune and reproductive functions.

    Conclusions:

    • Accurate diagnosis of selenosis requires a comprehensive understanding of both acute and chronic effects.
    • Environmental factors and interactions with other dietary components are critical in managing potential selenium toxicity cases.
    • Economic losses from chronic selenosis stem significantly from immune and reproductive system damage.