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The Mouse Gene Expression Database (GXD)
M Ringwald1, J T Eppig, D A Begley
1The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA. ringwald@informatics.jax.org
Nucleic Acids Research
|January 11, 2000
Summary
The Gene Expression Database (GXD) offers comprehensive mouse gene expression data. This resource aids researchers in understanding gene networks crucial for development and disease research.
Area of Science:
- Genomics
- Bioinformatics
- Developmental Biology
Background:
- The Gene Expression Database (GXD) is a vital community resource for mouse gene expression data.
- Understanding gene expression patterns is crucial for studying normal development and disease pathogenesis.
Purpose of the Study:
- To provide a comprehensive resource for gene expression information in laboratory mice.
- To enable insights into molecular networks underlying development and disease by integrating diverse expression data.
Main Methods:
- Integration of various gene expression data types.
- Interconnection with sequence databases and cross-species databases.
- Development and utilization of shared controlled vocabularies.
Main Results:
- GXD provides increasingly complete information on gene expression profiles.
- Facilitates analysis of gene expression across different mouse strains and mutants.
- Enables valuable insights into molecular networks.
Conclusions:
- GXD enhances the utility of gene expression information analysis.
- Integration with the Mouse Genome Database (MGD) and other resources expands its scope.
- Accessible online, GXD supports research in mouse genetics, development, and disease.