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Morphofunctional changes in the placenta after ozone therapy.

V M Andikyan1, I N Voloshchuk, P A Kovganko

  • 1Department of Pathological Anatomy, Therapeutic Faculty, IM Setchenov Moscow Medical Academy.

Bulletin of Experimental Biology and Medicine
|January 5, 2001
PubMed
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Ozone therapy improved placental morphology in women with insufficiency. It stimulated terminal villi growth and differentiation, potentially enhancing placental function.

Area of Science:

  • Obstetrics and Gynecology
  • Perinatology
  • Biomedical Research

Background:

  • Placental insufficiency affects pregnancy outcomes.
  • Ozone therapy is an alternative treatment modality.

Purpose of the Study:

  • To investigate placental morphology changes following ozone therapy in patients with placental insufficiency.
  • To compare these changes with a control group.

Main Methods:

  • Morphological examination (macro- and microscopic) of placentas from pregnant women with placental insufficiency.
  • Comparison between a group receiving ozone therapy and a control group.

Main Results:

  • Placentas in the ozone therapy group were smaller and weighed less compared to controls.

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  • Ozone therapy led to the enlargement of terminal villi with true syncytiocapillary membranes.
  • A stimulating effect of ozone therapy on terminal villi growth and differentiation was observed.

    • Conclusions:

    • Ozone therapy demonstrates a positive impact on placental morphology.
    • The therapy appears to stimulate growth and differentiation of placental villi.
    • Further research into ozone therapy for placental insufficiency is warranted.