Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Basic principles and therapy of spasticity].

V Dietz1

  • 1ParaCare, Universitätsklinik Balgrist, Zürich. dietz@balgrist.unizh.ch

Therapeutische Umschau. Revue Therapeutique
|January 6, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interactions between descending and spinal circuits on motor output.

Experimental neurology·2025
Same author

Spatiotemporal activation of lumbar sensorimotor networks.

Experimental neurology·2025
Same author

Coordination of bilateral synchronous and asynchronous hand movements.

Neuroscience letters·2020
Same author

Surgical management of pelvic organ prolapse.

Climacteric : the journal of the International Menopause Society·2018
Same author

Cooperative hand movements in tetraplegic spinal cord injury patients: Preserved neural coupling.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2018
Same author

Automatic gain control of neural coupling during cooperative hand movements.

Scientific reports·2018
Same journal

[Multimodal Cardiac Imaging: New Developments for Clinical Practice].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Coronary angiography: From cardiac catheterization to advanced interventional cardiovascular imaging].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Athlete's heart: role of cardiac imaging in the prevention of sudden cardiac death].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Multimodal imaging in cardiac amyloidosis and cardiac sarcoidosis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

[Inflammatory Heart Disease: The Role of Multimodality Cardiac Imaging in Myocarditis and Pericarditis].

Therapeutische Umschau. Revue therapeutique·2026
Same journal

State-of-the-Art Cardiac Imaging

Therapeutische Umschau. Revue therapeutique·2026
See all related articles

Following acute central nervous system lesions, spastic paresis develops due to muscle property changes, not reflexes. Specific treatments targeting these muscle changes are crucial for managing spastic movement disorders.

Area of Science:

  • Neuroscience
  • Neurology
  • Muscle Physiology

Context:

  • Acute central nervous system (CNS) lesions initially cause a "shock" phase with flaccid muscle tone.
  • Following this initial phase, spastic paresis emerges, characterized by increased muscle tone and hyperactive tendon reflexes.

Purpose:

  • To investigate the primary drivers of spastic movement disorders post-CNS lesion.
  • To differentiate the contribution of muscle property changes versus exaggerated reflexes to spasticity.

Summary:

  • Spastic movement disorders following CNS lesions are predominantly caused by secondary alterations in muscle properties.
  • Exaggerated tendon reflexes play a minimal role in the overall movement disorder.

Impact:

Related Experiment Videos

  • Highlights the necessity of treatments targeting muscle property changes for effective spasticity management.
  • Reorients therapeutic strategies away from solely addressing reflexes towards addressing underlying muscle pathophysiology.