Control of hypertension in postoperative patients
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Updated: Oct 10, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
X H Meng1, K Y Zhu, S M Krishnan
1School of Electronic and Electrical Engineering, Nanyang Technological University, Singapore 639798.
Abstract:
In this paper, adaptive control systems have been developed for the closed-loop control of mean arterial pressure using vasoactive drugs. An adaptive algorithm based on generalized predictive control law has been presented. A adaptive PI controller has been designed. The recursive least-square identification algorithm is used for on-line parameter estimation. The supervisor is added to provide safety and efficacy of control under the consideration of the physical and physiological constraints. Extensive computer simulation in the presence of unpredictable disturbances shows the system is capable of inducing hypertension.
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