Related Experiment Videos
Biomesogenic matrix systems
W V Meister1, S Lindau, A L Hauser
1Martin Luther University Halle-Wittenberg, Institute of Biochemistry, Saale, Germany. meister@biochemtech.uni-halle.de
Journal of Biomolecular Structure & Dynamics
|January 10, 2001
Abstract:
The bifunctionally reactive nucleoside and distant nucleoside analogs adenosine (Ado), S-[(adenine-9-yl)methoxyethyl]-L-cysteine (Na-salt) (cysA) and 9-vinyladenine (vA) in aqueous solutions assemble on complementary polyuridylic acid templates to form complex lyomesophases. The systems are investigated by polarizing microscopy, differential scanning calorimetry (DSC) and 1H- and 31P-nmr spectroscopies, assisted by molecular modeling studies. The results indicate the importance of biomesogenic (pre)ordering in nucleic acid native and artificial matrix reactions.